| 名稱(chēng) | LIGHT/CHO |
| 型號(hào) | CBP74029 |
| 報(bào)價(jià) |  |
| 特點(diǎn) | LIGHT/CHO，凍存條件：90% FBS+10% DMSO； |
產(chǎn)品搜索
產(chǎn)品分類(lèi)
相關(guān)文章
- VKORC1基因多態(tài)性用藥指導(dǎo)標(biāo)準(zhǔn)品
- 【連載-企業(yè)參考品】 前列腺癌的診斷參考品的選擇
- 從人結(jié)腸癌細(xì)胞株延伸出早期結(jié)腸癌治療方法
- CSF1R細(xì)胞篩選模型
- 假病毒標(biāo)準(zhǔn)品
- 官宣！Ba/F3激酶穩(wěn)定細(xì)胞株&科佰激酶篩選平臺(tái)
- 長(zhǎng)期研究使用的腦癌細(xì)胞系或面臨“身份危機(jī)”
- 【新品上線】一種安全高效的中和抗體體外篩選模型
- 【產(chǎn)品推介】CD47&SIRPɑ 細(xì)胞篩選模型
- atcc細(xì)胞庫(kù)的常見(jiàn)冷藏技術(shù)簡(jiǎn)介
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
電話：4008750250
號(hào)碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號(hào)
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > 腫瘤免疫細(xì)胞株 > CBP74029LIGHT/CHO
- 詳細(xì)內(nèi)容
| CBP74029 | |
| I. Background | |
| LIGHT (TNFSF14) is a key component of the communication system that controls the responses of T-Cells. LIGHT activates two cell surface receptors, the Herpesvirus Entry Mediator (HVEM) and the Lymphotoxin-beta Receptor (LTβR). The LIGHT-HVEM axis is an important costimulatory pathway for T cells, it has been shown to activate NF-κB; LIGHT/HVEM pair are co-stimulatory immune checkpoint molecules for cancer immunotherapy, LIGHT expressing cells have been shown to be more potent than the soluble LIGHT for activating HVEM expressed on T cell surface. | |
| II. Description | |
| Recombinant stable clonal CHO cell line constitutively expressing full length human LIGHT protein, also known as TNFSF14, (Genbank #NM_003807). Surface expression is confirmed by flow cytometry. | |
| III. Introduction | |
| Host Cell: | CHO, Chinese Hamster Ovary |
| Expressed gene: | Light |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Synonym(s): | TNFSF14, light cho |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | F12K+10%FBS+300ug/ml hygromycin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Ligand of HVEM&Binding Assay, FACS |
| IV. Description of Host Cell Line | |
| Organism: | Cricetulus griseus, hamster, Chinese |
| Tissue: | Ovary |
| Disease: | Normal |
| Morphology: | Epitheloid cell |
| Growth Properties: | Adherent |
| Ⅴ. Representative Data | |
| |
Figure. Recombinant stable clonal CHO cell line constitutively expressing full length human LIGHT protein, also known as TNFSF14, (Genbank #NM_003807). Surface expression is confirmed by flow cytometry. | |
會(huì)員_a.png)