| 名稱 | TP53 p.RRCPHHERC174fs Reference Standard 標(biāo)準(zhǔn)品 |
| 型號 | CBP10462 |
| 報價 |  |
| 特點(diǎn) | TP53 p.RRCPHHERC174fs Reference Standard |
產(chǎn)品搜索
相關(guān)文章
- 自身免疫疾病潛力靶點(diǎn)——IL-5藥篩細(xì)胞模型
- 能量平衡的重要靶點(diǎn)——CRF1R和CRF2R
- IgE：過敏與免疫的“雙面分子”
- 有關(guān)腫瘤細(xì)胞的基因突變研究講解
- 【產(chǎn)品推介】NRAS診斷標(biāo)準(zhǔn)品
- 細(xì)胞株鑒定指南
- 【新品發(fā)布】MRD標(biāo)準(zhǔn)品_40+位點(diǎn)panel標(biāo)準(zhǔn)品
- PNAS：腫瘤細(xì)胞或可“拆用”間充質(zhì)干細(xì)胞來促進(jìn)乳腺癌復(fù)發(fā)
- LTβR信號通路誘導(dǎo)三級淋巴結(jié)構(gòu)的形成，促進(jìn)趨化因子的表達(dá)
- 【連載-企業(yè)參考品】胃腸道間質(zhì)瘤的PCR和NGS參考品的選擇
聯(lián)系我們
聯(lián)系人：蔣經(jīng)理
電話：4008750250
號碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： zhangxiangwen@cobioer.com
電話：4008750250
號碼：
手機(jī)：18066071954
地址：南京市棲霞區(qū)緯地路9號
Email： zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
基因檢測標(biāo)準(zhǔn)品 > Mutation > CBP10462TP53 p.RRCPHHERC174fs Reference Standard 標(biāo)準(zhǔn)品
- 詳細(xì)內(nèi)容
CBP10462 | |
| Gene | TP53 |
| Description | TP53, cellular tumor antigen p53, is a tumor suppressor (PMID: 30562755) involved in cell cycle arrest and apoptosis, and is the most frequently mutated gene in cancer (PMID: 10065147, PMID: 22713868). TP53 germline mutations are common in Li-Fraumeni syndrome (PMID: 30239254) and somatic missense mutations are frequent in almost all cancer types cancers (PMID: 30224644) and are also implicated in chemoresistance (PMID: 9927204, PMID: 24065105, PMID: 27066457). |
| Technical Data | |
| DNA Change | c.520_545del |
| AA Change | p.RRCPHHERC174fs |
| Mutation type | Frame_Shift_Del |
| Zygosity | Heterozygous |
| Allelic Frequency | 50% |
| Transcript | ENST00000420246.2 |
| Cosmic ID | N/A |
| Chr position(GRCh37) | chr17:7578385_7578410 |
| Buffer | Tris-EDTA |
| Product Information | |
| Intended Use | Research Use Only |
| Unit Size | 1ug |
| Concentration | Download for COA |
| Purofication | Download for COA |
| DNA electrophoresis | Download for COA |
| Sanger sequencing | Download for COA |
| Storage | 4℃ |
| Expiry | 36 months from the date of manufacture |
