產(chǎn)品搜索
相關(guān)文章
- 【產(chǎn)品推介】IL12細(xì)胞篩選模型
- 腫瘤細(xì)胞的生長受哪些因素的作用呢?
- 耳聾基因檢測標(biāo)準(zhǔn)品
- 有關(guān)腫瘤細(xì)胞的基因突變研究講解
- 5月是黑色素瘤意識月,盤點(diǎn)黑色素瘤研究進(jìn)展
- FLT3基因檢測標(biāo)準(zhǔn)品
- ATCC細(xì)胞株穩(wěn)定整合試驗(yàn)中的幾個(gè)關(guān)鍵因素
- HPV分子診斷標(biāo)準(zhǔn)品擴(kuò)容:精準(zhǔn)檢測,實(shí)力升級
- THR-β激動(dòng)劑:NASH治療的新希望?
- 【產(chǎn)品推介】IL23抗體篩選模型
聯(lián)系我們
電話:4008750250
號碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號
Email: zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73255CSF3R S783fs/BaF3

- 詳細(xì)內(nèi)容
CBP73255 | |
I. Introduction | |
Cell Line Name: | CSF3R S783fs/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
II.Background | |
CSF3R S783fs results in a change in the amino acid sequence of the Csf3r protein beginning at aa 783 of 836, likely resulting in premature truncation of the functional protein (UniProt.org). S783fs does not result in increased Stat3 activation (PMID: 23656643, PMID: 24403076), however, results in increased Src activation and transformation in cell culture (PMID: 23656643), and therefore, is predicted to result in a gain of Csf3r protein function. | |
III. Representative Data | |
1.WB of CSF3R S783fs/BaF3 | |
2. Anti-proliferation assay | |
Figure 2. Anti-proliferation assay of three reference compounds on the CSF3R S783fs/BaF3. |