產(chǎn)品搜索
相關(guān)文章
- 剖析正常細(xì)胞是如何成長(zhǎng)為腫瘤細(xì)胞的
- 長(zhǎng)期研究使用的腦癌細(xì)胞系或面臨“身份危機(jī)”
- PLoS ONE:科學(xué)家發(fā)現(xiàn)癌癥轉(zhuǎn)移的新線索
- CTNNB1基因診斷標(biāo)準(zhǔn)品
- AKT E17K突變抑制劑細(xì)胞篩選模型介紹
- 熒光素酶檢測(cè)試劑盒介紹
- KIR3DL3/HHLA2細(xì)胞篩選模型
- 【產(chǎn)品推介】腫瘤耐藥細(xì)胞株
- 細(xì)胞株培養(yǎng)對(duì)于培養(yǎng)液的要求及相關(guān)常識(shí)說明
- 【新品上線】FGFR診斷標(biāo)準(zhǔn)品
聯(lián)系我們
電話:4008750250
號(hào)碼:
手機(jī):18066071954
地址:南京市棲霞區(qū)緯地路9號(hào)
Email: zhangxiangwen@cobioer.com
產(chǎn)品展示 / PRODUCTS
藥靶細(xì)胞株 > kinase激酶細(xì)胞株 > CBP73255CSF3R S783fs/BaF3

- 詳細(xì)內(nèi)容
CBP73255 | |
I. Introduction | |
Cell Line Name: | CSF3R S783fs/BaF3 |
Host Cell: | Ba/F3 |
Stability: | 16 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Application: | Anti-proliferation assay and PD assay |
Freeze Medium: | 90% FBS+10% DMSO |
Complete Culture Medium: | RPMI-1640+10%FBS |
Mycoplasma Status: | Negative |
II.Background | |
CSF3R S783fs results in a change in the amino acid sequence of the Csf3r protein beginning at aa 783 of 836, likely resulting in premature truncation of the functional protein (UniProt.org). S783fs does not result in increased Stat3 activation (PMID: 23656643, PMID: 24403076), however, results in increased Src activation and transformation in cell culture (PMID: 23656643), and therefore, is predicted to result in a gain of Csf3r protein function. | |
III. Representative Data | |
1.WB of CSF3R S783fs/BaF3 | |
2. Anti-proliferation assay | |
Figure 2. Anti-proliferation assay of three reference compounds on the CSF3R S783fs/BaF3. |